Product Data Sheet

SARS-CoV-2 Mpro-IN-9

Catalog No. A53398

main product photo
SARS-CoV-2 Mpro-IN-9 is a nonpeptidic, noncovalent inhibitor targeting the main protease (Mpro) of SARS-CoV-2, exhibiting an IC50 of 0.085 μM. This compound demonstrates effective inhibition of viral replication in SARS-CoV-2-infected Vero E6 cells, with an EC50 of 1.10 μM, while showing low cytotoxicity (CC50 > 50 μM). SARS-CoV-2 Mpro-IN-9 is significant for research applications focused on antiviral strategies against COVID-19 and the development of therapeutic agents.
Chemical Information
Catalog NumA53398
M. Wt346.34
FormulaC20H14N2O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2754370-99-3
Synonyms
SMILESO=C1N(C2=CC=CC=C2)C(C3=CC=CC=C3)=NC4=C1C(O)=C(O)C(O)=C4
Biological Activity
DescriptionSARS-CoV-2 Mpro-IN-9 is a nonpeptidic, noncovalent inhibitor targeting the main protease (Mpro) of SARS-CoV-2, exhibiting an IC50 of 0.085 μM. This compound demonstrates effective inhibition of viral replication in SARS-CoV-2-infected Vero E6 cells, with an EC50 of 1.10 μM, while showing low cytotoxicity (CC50 > 50 μM). SARS-CoV-2 Mpro-IN-9 is significant for research applications focused on antiviral strategies against COVID-19 and the development of therapeutic agents.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.