Product Data Sheet

ZINC61142882

Catalog No. A53408

main product photo
ZINC61142882 is an inhibitor of the SARS-CoV-2 Nsp14 N7-Methyltransferase, exhibiting an IC50 value of 6 μM. This compound demonstrates antiviral activity by disrupting viral RNA cap methylation, which is essential for RNA stability and immune evasion. It is suitable for research focused on COVID-19 therapeutic development and the exploration of viral RNA modifications.
Chemical Information
Catalog NumA53408
M. Wt387.19
FormulaC16H11BrN4O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3034181-87-5
Synonyms
SMILESO=C(C1=NNC(C2=CC=CO2)=C1)OCC3=CN4C(C=CC(Br)=C4)=N3
Biological Activity
DescriptionZINC61142882 is an inhibitor of the SARS-CoV-2 Nsp14 N7-Methyltransferase, exhibiting an IC50 value of 6 μM. This compound demonstrates antiviral activity by disrupting viral RNA cap methylation, which is essential for RNA stability and immune evasion. It is suitable for research focused on COVID-19 therapeutic development and the exploration of viral RNA modifications.
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