Product Data Sheet
MWAC-3429
Catalog No. A53444
MWAC-3429 is a potent inhibitor of the SARS-CoV-2 Nsp13 helicase, demonstrating robust antiviral activity against both SARS-CoV-2 and SARS-CoV-1. With EC50 values of 5.39 μM (nLuc assay) and 17.00 μM (CPE assay), MWAC-3429 exhibits low cytotoxicity in A549-hACE2 cells, with a CC50 greater than 50 μM. This compound is valuable for research into SARS-CoV infections and the mechanistic understanding of viral helicase inhibition.
Chemical Information
| Catalog Num | A53444 |
|---|---|
| M. Wt | 393.50 |
| Formula | C22H23N3O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2093677-54-2 |
| Synonyms | |
| SMILES | COC1=CC2=C(CC(N(C2)C(C3=CSC(CCN)=N3)=O)C4=CC=CC=C4)C=C1 |
Biological Activity
| Description | MWAC-3429 is a potent inhibitor of the SARS-CoV-2 Nsp13 helicase, demonstrating robust antiviral activity against both SARS-CoV-2 and SARS-CoV-1. With EC50 values of 5.39 μM (nLuc assay) and 17.00 μM (CPE assay), MWAC-3429 exhibits low cytotoxicity in A549-hACE2 cells, with a CC50 greater than 50 μM. This compound is valuable for research into SARS-CoV infections and the mechanistic understanding of viral helicase inhibition. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
