SARS-CoV-2-IN-97
Catalog No. A53464

SARS-CoV-2-IN-97 is a specific inhibitor targeting the SARS-CoV-2 Nsp15 endoribonuclease, demonstrating an IC50 of 53.5 μM. This compound shows low cytotoxicity in A549-AT cells, with an IC50 of 134 μM, making it a valuable tool for studying SARS-CoV-2 biology and antiviral strategies. Its selective inhibition could aid in the development of therapeutic approaches against COVID-19.
Chemical Information
| Catalog Num | A53464 |
|---|---|
| M. Wt | 352.97 |
| Formula | C11H3Br2N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 364338-71-6 |
| Synonyms | |
| SMILES | BrC1=CC(Br)=CC2=C1NC(/C2=C(C#N)\C#N)=O |
Biological Activity
| Description | SARS-CoV-2-IN-97 is a specific inhibitor targeting the SARS-CoV-2 Nsp15 endoribonuclease, demonstrating an IC50 of 53.5 μM. This compound shows low cytotoxicity in A549-AT cells, with an IC50 of 134 μM, making it a valuable tool for studying SARS-CoV-2 biology and antiviral strategies. Its selective inhibition could aid in the development of therapeutic approaches against COVID-19. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


