Product Data Sheet
AG-7404
Catalog No. A53568
AG-7404 is an orally active, irreversible inhibitor of the picornavirus 3C protease, which disrupts the processing of viral polyproteins and effectively inhibits viral replication. This compound demonstrates synergistic antiviral activity when used alongside capsid inhibitors, making it valuable for research on enterovirus infections, including poliovirus. AG-7404 is particularly useful in studies involving V-073-resistant viral variants, contributing to a deeper understanding of antiviral mechanisms and potential therapies.
Chemical Information
| Catalog Num | A53568 |
|---|---|
| M. Wt | 523.54 |
| Formula | C26H29N5O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 343565-99-1 |
| Synonyms | |
| SMILES | O=C(NCC1)[C@@H]1C[C@@H](/C=C/C(OCC)=O)NC([C@@H](N2C(C(NC(C3=NOC(C)=C3)=O)=CC=C2)=O)CC#C)=O |
Biological Activity
| Description | AG-7404 is an orally active, irreversible inhibitor of the picornavirus 3C protease, which disrupts the processing of viral polyproteins and effectively inhibits viral replication. This compound demonstrates synergistic antiviral activity when used alongside capsid inhibitors, making it valuable for research on enterovirus infections, including poliovirus. AG-7404 is particularly useful in studies involving V-073-resistant viral variants, contributing to a deeper understanding of antiviral mechanisms and potential therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
