Product Data Sheet

NS2B/NS3-IN-6

Catalog No. A53603

main product photo
NS2B/NS3-IN-6 is an allosteric inhibitor targeting the NS2B/NS3 protease of Dengue virus (DENV) and Zika virus (ZIKV). It exhibits IC50 values of 2.23 µM and 25.2 µM against ZIKV and DENV proteases, respectively. This compound is valuable for research applications focused on developing antiviral therapies and understanding the enzymatic mechanisms of flavivirus proteases.
Chemical Information
Catalog NumA53603
M. Wt433.50
FormulaC19H19N3O5S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2459657-57-7
Synonyms
SMILESO=S(N1[C@@H](CCC1)C(NC2=NC3=CC(O)=C(O)C=C3S2)=O)(C4=CC=C(C=C4)C)=O
Biological Activity
DescriptionNS2B/NS3-IN-6 is an allosteric inhibitor targeting the NS2B/NS3 protease of Dengue virus (DENV) and Zika virus (ZIKV). It exhibits IC50 values of 2.23 µM and 25.2 µM against ZIKV and DENV proteases, respectively. This compound is valuable for research applications focused on developing antiviral therapies and understanding the enzymatic mechanisms of flavivirus proteases.
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