Product Data Sheet
ANG1005
Catalog No. A53638
ANG1005 is a peptide-paclitaxel conjugate designed to enhance brain delivery through targeted transport mechanisms. By covalently linking three paclitaxel molecules to Angiopep-2, ANG1005 effectively utilizes the low-density lipoprotein receptor-related protein (LRP1) pathway to cross the blood-brain and blood-cerebrospinal barriers. This innovative compound exhibits potent cytotoxicity against malignant cells, making it a valuable tool for research in brain tumor therapeutics and assessing drug delivery systems in neuro-oncology.
Chemical Information
| Catalog Num | A53638 |
|---|---|
| M. Wt | 5109.36 |
| Formula | C257H308N32O79 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1075214-55-9 |
| Synonyms | GRN1005; Paclitaxel trevatide |
| SMILES |
Biological Activity
| Description | ANG1005 is a peptide-paclitaxel conjugate designed to enhance brain delivery through targeted transport mechanisms. By covalently linking three paclitaxel molecules to Angiopep-2, ANG1005 effectively utilizes the low-density lipoprotein receptor-related protein (LRP1) pathway to cross the blood-brain and blood-cerebrospinal barriers. This innovative compound exhibits potent cytotoxicity against malignant cells, making it a valuable tool for research in brain tumor therapeutics and assessing drug delivery systems in neuro-oncology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
