Product Data Sheet

LOC1886

Catalog No. A53772

main product photo
LOC1886 is a covalent inhibitor targeting glutathione peroxidase 4 (GPX4), crucial for regulating oxidative stress within cells. It exhibits robust biological activity that aids in the investigation of ferroptosis and related cell death pathways. This compound is particularly useful for research applications focused on cancer biology, neurodegenerative diseases, and the study of oxidative damage mechanisms.
Chemical Information
Catalog NumA53772
M. Wt241.25
FormulaC13H11N3O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.951948-38-2
Synonyms
SMILESO=C(N1C=NC=C1)C2=CC3=C(N2)C=CC=C3OC
Biological Activity
DescriptionLOC1886 is a covalent inhibitor targeting glutathione peroxidase 4 (GPX4), crucial for regulating oxidative stress within cells. It exhibits robust biological activity that aids in the investigation of ferroptosis and related cell death pathways. This compound is particularly useful for research applications focused on cancer biology, neurodegenerative diseases, and the study of oxidative damage mechanisms.
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SHIPPING AND STORAGE
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