Product Data Sheet
WK298
Catalog No. A53877
WK298 is a potent small molecule inhibitor targeting the MDM2/MDMX-p53 interaction. By preventing the binding of MDM2 and MDMX to p53, WK298 effectively activates the p53 signaling pathway, leading to significant anti-tumor activity. This compound is valuable for research applications focused on cancer biology and the therapeutic modulation of p53-mediated pathways.
Chemical Information
| Catalog Num | A53877 |
|---|---|
| M. Wt | 629.62 |
| Formula | C35H38Cl2N6O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1067654-70-9 |
| Synonyms | |
| SMILES | O=C(N1C[C@H](CC1)N(C)CCCN(C)C)C2=C(C3=C(C4=CC=CC=C4)N=CN3CC5=CC=C(C=C5)Cl)C6=CC=C(Cl)C=C6N2 |
Biological Activity
| Description | WK298 is a potent small molecule inhibitor targeting the MDM2/MDMX-p53 interaction. By preventing the binding of MDM2 and MDMX to p53, WK298 effectively activates the p53 signaling pathway, leading to significant anti-tumor activity. This compound is valuable for research applications focused on cancer biology and the therapeutic modulation of p53-mediated pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
