Product Data Sheet
S100A2-p53-IN-1
Catalog No. A53890
S100A2-p53-IN-1 is a specific inhibitor of the S100A2-p53 protein interaction. S100A2, a calcium-binding protein, plays a significant role in cell signaling and is upregulated in pancreatic cancer. This compound demonstrates potent inhibitory activity against the MiaPaCa-2 pancreatic cancer cell line, achieving a growth inhibition concentration (GI50) in the range of 1.2-3.4 μM. It serves as a valuable tool for investigating the S100A2-p53 pathway in cancer research.
Chemical Information
| Catalog Num | A53890 |
|---|---|
| M. Wt | 498.44 |
| Formula | C20H20F6N2O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2766609-08-7 |
| Synonyms | |
| SMILES | O=S(NCCCNCC1COC2=C(O1)C=CC=C2)(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)=O |
Biological Activity
| Description | S100A2-p53-IN-1 is a specific inhibitor of the S100A2-p53 protein interaction. S100A2, a calcium-binding protein, plays a significant role in cell signaling and is upregulated in pancreatic cancer. This compound demonstrates potent inhibitory activity against the MiaPaCa-2 pancreatic cancer cell line, achieving a growth inhibition concentration (GI50) in the range of 1.2-3.4 μM. It serves as a valuable tool for investigating the S100A2-p53 pathway in cancer research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
