Product Data Sheet

MDM2-IN-26

Catalog No. A53903

main product photo
MDM2-IN-26 is an inhibitor targeting MDM2, a critical negative regulator of the tumor suppressor p53. By disrupting the MDM2-p53 interaction, this compound effectively activates p53's tumor suppressor functions, providing a promising approach for cancer research. MDM2-IN-26 can be utilized to study the modulation of p53 activity in various cancer models and therapeutic applications.
Chemical Information
Catalog NumA53903
M. Wt650.52
FormulaC32H32Cl2F3N3O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1818393-11-1
Synonyms
SMILESOC(C12CCC(CC2)(NC([C@H]3[C@H](C4=CC=CC(Cl)=C4F)[C@@]5(C(C=CC(Cl)=C6)=C6NC5=O)C7(CCC(F)(F)CC7)N3)=O)CC1)=O
Biological Activity
DescriptionMDM2-IN-26 is an inhibitor targeting MDM2, a critical negative regulator of the tumor suppressor p53. By disrupting the MDM2-p53 interaction, this compound effectively activates p53's tumor suppressor functions, providing a promising approach for cancer research. MDM2-IN-26 can be utilized to study the modulation of p53 activity in various cancer models and therapeutic applications.
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