Product Data Sheet
MDM2-p53-IN-20
Catalog No. A53916
MDM2-p53-IN-20 is a synthetic inhibitor targeting the MDM2-p53 protein interaction. This compound disrupts the binding of MDM2 to p53, promoting the stabilization and activation of p53, a critical tumor suppressor involved in cell cycle regulation and apoptosis. MDM2-p53-IN-20 is primarily utilized in cancer research to study p53 pathway activation and to explore therapeutic strategies for tumors exhibiting MDM2 overexpression.
Chemical Information
| Catalog Num | A53916 |
|---|---|
| M. Wt | 685.48 |
| Formula | C32H27Cl2FN4O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2095120-09-3 |
| Synonyms | |
| SMILES | O=C(C1=C(C(C)=C(C=C1)C(OC)=O)[N+]([O-])=O)C[C@H]2[C@@H]([N+]([O-])=O)[C@H](C3=C(C(Cl)=CC=C3)F)[C@@]4(C5=CC=C(Cl)C=C5NC4=O)N2CC6CC6 |
Biological Activity
| Description | MDM2-p53-IN-20 is a synthetic inhibitor targeting the MDM2-p53 protein interaction. This compound disrupts the binding of MDM2 to p53, promoting the stabilization and activation of p53, a critical tumor suppressor involved in cell cycle regulation and apoptosis. MDM2-p53-IN-20 is primarily utilized in cancer research to study p53 pathway activation and to explore therapeutic strategies for tumors exhibiting MDM2 overexpression. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
