Product Data Sheet

Azalamellarin N

Catalog No. A53970

main product photo
Azalamellarin N is a selective inhibitor of pyroptosis, effectively modulating the inflammatory response by targeting upstream signaling pathways involved in NLRP3 inflammasome activation. This compound exhibits differential inhibitory effects on various pyroptosis inducers, with notable potency against Nigericin and R837. Its mechanism provides a valuable tool for investigating the role of pyroptosis in cellular processes and disease states, making it significant for research in inflammation and immune responses.
Chemical Information
Catalog NumA53970
M. Wt498.48
FormulaC28H22N2O7
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1809535-57-6
SynonymsAZL-N
SMILESOC1=CC(C2=C(C(C=C(OC)C(O)=C3)=C3C=C4)N4C5=C2C6=C(C=C(O)C(OC)=C6)NC5=O)=CC=C1OC
Biological Activity
DescriptionAzalamellarin N is a selective inhibitor of pyroptosis, effectively modulating the inflammatory response by targeting upstream signaling pathways involved in NLRP3 inflammasome activation. This compound exhibits differential inhibitory effects on various pyroptosis inducers, with notable potency against Nigericin and R837. Its mechanism provides a valuable tool for investigating the role of pyroptosis in cellular processes and disease states, making it significant for research in inflammation and immune responses.
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SHIPPING AND STORAGE
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