Product Data Sheet
Edatrexate
Catalog No. A54039
Edatrexate, an antifolate agent, is a potent analog of Methotrexate that exhibits significant antitumor activity against MTX-resistant tumors. This compound functions as an antimetabolite, effectively inhibiting folate metabolism, thereby disrupting proliferation in cancer cells. Edatrexate is particularly relevant in research applications for non-small-cell lung cancer, breast cancer, non-Hodgkin's lymphoma, and cancers of the head and neck.
Chemical Information
| Catalog Num | A54039 |
|---|---|
| M. Wt | 467.48 |
| Formula | C22H25N7O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 80576-83-6 |
| Synonyms | CGP 30694 |
| SMILES | O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(C(CC2=NC3=C(N)N=C(N)N=C3N=C2)CC)C=C1)=O |
Biological Activity
| Description | Edatrexate, an antifolate agent, is a potent analog of Methotrexate that exhibits significant antitumor activity against MTX-resistant tumors. This compound functions as an antimetabolite, effectively inhibiting folate metabolism, thereby disrupting proliferation in cancer cells. Edatrexate is particularly relevant in research applications for non-small-cell lung cancer, breast cancer, non-Hodgkin's lymphoma, and cancers of the head and neck. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
