Pyr-Pro-Arg-pNA hydrochloride
Catalog No. A54067

Pyr-Pro-Arg-pNA hydrochloride is a chromogenic peptide substrate primarily targeting Factor XI and Activated Protein C (APC). It serves as a noncompetitive inhibitor of factor XI activation by binding to the active site of the factor XIa-light chain. This compound is essential for quantifying APC amidolytic activity in various biological assays, making it a valuable tool in coagulation research.
Chemical Information
| Catalog Num | A54067 |
|---|---|
| M. Wt | 538.98 |
| Formula | C22H31ClN8O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 127428-47-1 |
| Synonyms | S-2366 hydrochloride |
| SMILES | [O-][N+](C(C=C1)=CC=C1NC([C@H](CCCNC(N)=N)NC([C@H](CCC2)N2C([C@@H]3CCC(N3)=O)=O)=O)=O)=O.Cl |
Biological Activity
| Description | Pyr-Pro-Arg-pNA hydrochloride is a chromogenic peptide substrate primarily targeting Factor XI and Activated Protein C (APC). It serves as a noncompetitive inhibitor of factor XI activation by binding to the active site of the factor XIa-light chain. This compound is essential for quantifying APC amidolytic activity in various biological assays, making it a valuable tool in coagulation research. |
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RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


