Product Data Sheet

BML-259

Catalog No. A54168

main product photo
BML-259 is a potent inhibitor of cyclin-dependent kinase 5 (Cdk5), exhibiting IC50 values of 64 nM and 98 nM for Cdk5 and Cdk2, respectively. This compound is valuable in research focused on neurodegenerative diseases and neuronal signaling pathways since Cdk5 plays a critical role in neuronal development and function. Its selective inhibition can enhance understanding of Cdk5-related mechanisms and potential therapeutic applications.
Chemical Information
Catalog NumA54168
M. Wt260.35
FormulaC14H16N2OS
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.267654-00-2
Synonyms
SMILESO=C(NC1=NC=C(C(C)C)S1)CC2=CC=CC=C2
Biological Activity
DescriptionBML-259 is a potent inhibitor of cyclin-dependent kinase 5 (Cdk5), exhibiting IC50 values of 64 nM and 98 nM for Cdk5 and Cdk2, respectively. This compound is valuable in research focused on neurodegenerative diseases and neuronal signaling pathways since Cdk5 plays a critical role in neuronal development and function. Its selective inhibition can enhance understanding of Cdk5-related mechanisms and potential therapeutic applications.
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