Product Data Sheet
CDK9-IN-13
Catalog No. A54186
CDK9-IN-13 is a potent and selective inhibitor of cyclin-dependent kinase 9 (CDK9), exhibiting an IC50 value of less than 3 nM. This compound effectively modulates transcriptional regulation by inhibiting CDK9's role in phosphorylating the RNA polymerase II elongation complex. Given its high potency, CDK9-IN-13 is a valuable tool for investigating the role of CDK9 in various cellular processes and its potential implications in cancer and other diseases.
Chemical Information
| Catalog Num | A54186 |
|---|---|
| M. Wt | 461.60 |
| Formula | C27H35N5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2768712-71-4 |
| Synonyms | |
| SMILES | CC(C)N1C=C(C2=CC=NC3=C2C=C(C4CCN(CC(N5CCCCC5)=O)CC4)N3)C=CC1=O |
Biological Activity
| Description | CDK9-IN-13 is a potent and selective inhibitor of cyclin-dependent kinase 9 (CDK9), exhibiting an IC50 value of less than 3 nM. This compound effectively modulates transcriptional regulation by inhibiting CDK9's role in phosphorylating the RNA polymerase II elongation complex. Given its high potency, CDK9-IN-13 is a valuable tool for investigating the role of CDK9 in various cellular processes and its potential implications in cancer and other diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
