Product Data Sheet
NSC 625987
Catalog No. A54237
NSC 625987 is a potent CDK4 inhibitor, exhibiting an IC50 of 0.2 μM for the CDK4:cyclin D1 complex. This compound demonstrates more than 500-fold selectivity for CDK4 compared to CDK2, making it a valuable tool for studying cell cycle regulation and cancer biology. Its specificity and efficacy make NSC 625987 suitable for research applications aimed at understanding CDK4's role in tumor proliferation and potential therapeutic strategies.
Chemical Information
| Catalog Num | A54237 |
|---|---|
| M. Wt | 271.33 |
| Formula | C15H13NO2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 141992-47-4 |
| Synonyms | |
| SMILES | S=C1C2=C(C=CC=C2)NC3=C(OC)C=CC(OC)=C13 |
Biological Activity
| Description | NSC 625987 is a potent CDK4 inhibitor, exhibiting an IC50 of 0.2 μM for the CDK4:cyclin D1 complex. This compound demonstrates more than 500-fold selectivity for CDK4 compared to CDK2, making it a valuable tool for studying cell cycle regulation and cancer biology. Its specificity and efficacy make NSC 625987 suitable for research applications aimed at understanding CDK4's role in tumor proliferation and potential therapeutic strategies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
