Product Data Sheet

(S)-(-)-O-Demethylbuchenavianine

Catalog No. A54269

main product photo
(S)-(-)-O-Demethylbuchenavianine is a flavonoidal alkaloid that functions as a potent inhibitor of cyclin-dependent kinases (CDKs), specifically targeting CDK1 and CDK5 with IC50 values of 0.03 and 0.05 μM, respectively. This compound is valuable for research applications focused on cell cycle regulation and the investigation of CDK-related signaling pathways. Its inhibitory activity makes it an important tool for studying the role of CDKs in various biological processes and diseases.
Chemical Information
Catalog NumA54269
M. Wt351.40
FormulaC21H21NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.91147-18-1
Synonyms
SMILESOC1=CC(O)=C(C(C=C(C2=CC=CC=C2)O3)=O)C3=C1[C@H]4N(CCCC4)C
Biological Activity
Description(S)-(-)-O-Demethylbuchenavianine is a flavonoidal alkaloid that functions as a potent inhibitor of cyclin-dependent kinases (CDKs), specifically targeting CDK1 and CDK5 with IC50 values of 0.03 and 0.05 μM, respectively. This compound is valuable for research applications focused on cell cycle regulation and the investigation of CDK-related signaling pathways. Its inhibitory activity makes it an important tool for studying the role of CDKs in various biological processes and diseases.
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SHIPPING AND STORAGE
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