Product Data Sheet

CDK7-IN-11

Catalog No. A54284

main product photo
CDK7-IN-11 is a potent inhibitor of cyclin-dependent kinase 7 (CDK7), demonstrating a high inhibitory activity with an IC50 value of 4.2 nM. This compound is suitable for in-depth research into diseases linked to CDK7 activity, providing valuable insights into its role in cell cycle regulation and transcriptional control. CDK7-IN-11 can aid in the exploration of therapeutic strategies targeting CDK7 in various malignancies and other pathological conditions.
Chemical Information
Catalog NumA54284
M. Wt488.60
FormulaC26H28N6O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2414896-32-3
Synonyms
SMILESN#CC1=CC(C2=CC([C@H](C)C(NC3=NC=C(CC)S3)=O)=CC=C2)=CN=C1NC(/C=C/CN(C)C)=O
Biological Activity
DescriptionCDK7-IN-11 is a potent inhibitor of cyclin-dependent kinase 7 (CDK7), demonstrating a high inhibitory activity with an IC50 value of 4.2 nM. This compound is suitable for in-depth research into diseases linked to CDK7 activity, providing valuable insights into its role in cell cycle regulation and transcriptional control. CDK7-IN-11 can aid in the exploration of therapeutic strategies targeting CDK7 in various malignancies and other pathological conditions.
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