Product Data Sheet
CDK9-IN-38
Catalog No. A54307
CDK9-IN-38 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9), exhibiting IC50 values of 1.2 nM for the wild-type enzyme and 3.3 nM for the L156F mutant variant. This compound has demonstrated significant inhibitory effects on tumor growth in both in vitro and in vivo models. CDK9-IN-38 is a valuable tool for research into the regulation of transcriptional control and the therapeutic potential for cancer treatment.
Chemical Information
| Catalog Num | A54307 |
|---|---|
| M. Wt | 437.51 |
| Formula | C22H23N5O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2773402-44-9 |
| Synonyms | |
| SMILES | O=C1NCC(C)(C)C2=CC(C3=NC(NC4=CC=CC(CS(N)(=O)=O)=C4)=NC=C3)=CC=C21 |
Biological Activity
| Description | CDK9-IN-38 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9), exhibiting IC50 values of 1.2 nM for the wild-type enzyme and 3.3 nM for the L156F mutant variant. This compound has demonstrated significant inhibitory effects on tumor growth in both in vitro and in vivo models. CDK9-IN-38 is a valuable tool for research into the regulation of transcriptional control and the therapeutic potential for cancer treatment. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
