Product Data Sheet

CDK4/6-IN-24

Catalog No. A54318

main product photo
CDK4/6-IN-24 is a potent inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6), key regulators of the cell cycle. This compound demonstrates broad-spectrum antitumor activity across various cancer cell lines, with IC50 values in the submicromolar range. CDK4/6-IN-24 is a valuable tool for researchers investigating cell cycle regulation and therapeutic strategies for cancer treatment.
Chemical Information
Catalog NumA54318
M. Wt571.71
FormulaC32H41N7O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2662813-96-7
Synonyms
SMILESO=C1N(C2CCCC2)C3=NC(NC4=CC=C(N5[C@](CN(C6CCN(CC6)C)CC5)([H])CO7)C7=C4)=NC=C3C(C)=C1C(C)=O
Biological Activity
DescriptionCDK4/6-IN-24 is a potent inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6), key regulators of the cell cycle. This compound demonstrates broad-spectrum antitumor activity across various cancer cell lines, with IC50 values in the submicromolar range. CDK4/6-IN-24 is a valuable tool for researchers investigating cell cycle regulation and therapeutic strategies for cancer treatment.
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