Product Data Sheet
(+)-Atuveciclib ((+)-BAY-1143572, d-BAY-1143572)
Catalog No. A54329
(+)-Atuveciclib is a selective inhibitor of cyclin-dependent kinase 9 (CDK9) and the positive transcription elongation factor b (P-TEFb). With an IC50 value of 13 nM, it effectively suppresses CDK9 in cellular assays. This compound is primarily utilized in research related to transcription regulation and cancer therapeutics, offering insights into CDK9-mediated pathways and their role in various malignancies.
Chemical Information
| Catalog Num | A54329 |
|---|---|
| M. Wt | 387.43 |
| Formula | C18H18FN5O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1414943-94-4 |
| Synonyms | (+)-BAY-1143572 |
| SMILES | COC1=C(C2=NC=NC(NC3=CC(CS(C)(=N)=O)=CC=C3)=N2)C=CC(F)=C1 |
Biological Activity
| Description | (+)-Atuveciclib is a selective inhibitor of cyclin-dependent kinase 9 (CDK9) and the positive transcription elongation factor b (P-TEFb). With an IC50 value of 13 nM, it effectively suppresses CDK9 in cellular assays. This compound is primarily utilized in research related to transcription regulation and cancer therapeutics, offering insights into CDK9-mediated pathways and their role in various malignancies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
