Product Data Sheet
CDK5-IN-2
Catalog No. A54341
CDK5-IN-2 is a highly selective cyclin-dependent kinase 5 (CDK5) inhibitor, exhibiting IC50 values of 0.2 nM against CDK5/p25 and 23 nM against CDK2/CycA. It serves as a valuable tool in research focused on neurodegenerative diseases, as CDK5 plays a critical role in neuronal function and development. This compound enables the exploration of CDK5's involvement in various cellular processes and its potential as a therapeutic target.
Chemical Information
| Catalog Num | A54341 |
|---|---|
| M. Wt | 481.56 |
| Formula | C29H28FN5O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2639542-22-4 |
| Synonyms | |
| SMILES | FC1=CC(C2=CC=CC(C#N)=C2)=CC=C1NC3=CC4=NC([C@](C)(O)C5CCN(C)CC5)=CC=C4C=N3 |
Biological Activity
| Description | CDK5-IN-2 is a highly selective cyclin-dependent kinase 5 (CDK5) inhibitor, exhibiting IC50 values of 0.2 nM against CDK5/p25 and 23 nM against CDK2/CycA. It serves as a valuable tool in research focused on neurodegenerative diseases, as CDK5 plays a critical role in neuronal function and development. This compound enables the exploration of CDK5's involvement in various cellular processes and its potential as a therapeutic target. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
