Product Data Sheet

CDK9-IN-15

Catalog No. A54352

main product photo
CDK9-IN-15 is a selective inhibitor of cyclin-dependent kinase 9 (CDK9), a key regulator of transcription elongation. By inhibiting CDK9, this compound effectively reduces the phosphorylation of RNA polymerase II, leading to decreased transcriptional activity of oncogenes. CDK9-IN-15 is primarily utilized in cancer research to explore therapeutic strategies that target transcriptional regulation in malignancies.
Chemical Information
Catalog NumA54352
M. Wt293.34
FormulaC16H11N3OS
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.852678-17-2
Synonyms
SMILESOC1=C2C=CC=C(NC3=C(C=CS4)C4=NC=N3)C2=CC=C1
Biological Activity
DescriptionCDK9-IN-15 is a selective inhibitor of cyclin-dependent kinase 9 (CDK9), a key regulator of transcription elongation. By inhibiting CDK9, this compound effectively reduces the phosphorylation of RNA polymerase II, leading to decreased transcriptional activity of oncogenes. CDK9-IN-15 is primarily utilized in cancer research to explore therapeutic strategies that target transcriptional regulation in malignancies.
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