Product Data Sheet

CDK2/4-IN-2

Catalog No. A54374

main product photo
CDK2/4-IN-2 is a potent dual inhibitor of cyclin-dependent kinases 2 and 4, exhibiting IC50 values below 100 nM. This compound is instrumental in cancer research, providing insights into cell cycle regulation and the therapeutic potential of targeting CDK pathways. Its efficacy in inhibiting CDK2 and CDK4 makes it a valuable reagent for investigating tumor cell proliferation and developing anti-cancer strategies.
Chemical Information
Catalog NumA54374
M. Wt503.52
FormulaC18H20F3N7O3S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3034898-59-1
Synonyms
SMILESO=S(C1=CNN=C1)(N2CCC(CC2)NC3=NC(C4=NC=C(C(C)O)S4)=C(C(F)(F)F)C=N3)=O
Biological Activity
DescriptionCDK2/4-IN-2 is a potent dual inhibitor of cyclin-dependent kinases 2 and 4, exhibiting IC50 values below 100 nM. This compound is instrumental in cancer research, providing insights into cell cycle regulation and the therapeutic potential of targeting CDK pathways. Its efficacy in inhibiting CDK2 and CDK4 makes it a valuable reagent for investigating tumor cell proliferation and developing anti-cancer strategies.
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