Product Data Sheet

CDK8-IN-18

Catalog No. A54412

main product photo
CDK8-IN-18 is a selective inhibitor of cyclin-dependent kinase 8 (CDK8) with an IC50 of 43 μM. This compound is instrumental in studying the regulatory roles of CDK8 in transcription and its implications in oncogenesis. CDK8-IN-18 is widely used in cancer research to explore the therapeutic potential of targeting CDK8 in malignancies.
Chemical Information
Catalog NumA54412
M. Wt266.34
FormulaC16H18N4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.642002-74-2
Synonyms
SMILESN#CC1=C(C2=CN=CC=C2)C(CC)=C(CCC)N=C1N
Biological Activity
DescriptionCDK8-IN-18 is a selective inhibitor of cyclin-dependent kinase 8 (CDK8) with an IC50 of 43 μM. This compound is instrumental in studying the regulatory roles of CDK8 in transcription and its implications in oncogenesis. CDK8-IN-18 is widely used in cancer research to explore the therapeutic potential of targeting CDK8 in malignancies.
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