Product Data Sheet

CDK4-IN-4

Catalog No. A54449

main product photo
CDK4-IN-4 is a selective inhibitor of Cyclin-dependent kinase 4 (CDK4), with an IC50 value of less than 10 nM. This compound plays a critical role in cancer research by selectively interfering with cell cycle regulation, thus inhibiting the proliferation of cancer cells. CDK4-IN-4 is suitable for studies focusing on cell cycle dynamics and the therapeutic potential of CDK4 inhibition in various cancer models.
Chemical Information
Catalog NumA54449
M. Wt457.93
FormulaC23H25ClFN5O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3027994-03-9
Synonyms
SMILESFC1=C2C(C3=C(CC(C)(NC3)C)C=N2)=CC(C4=NC(N[C@H]5[C@@H](COCC5)O)=NC=C4Cl)=C1
Biological Activity
DescriptionCDK4-IN-4 is a selective inhibitor of Cyclin-dependent kinase 4 (CDK4), with an IC50 value of less than 10 nM. This compound plays a critical role in cancer research by selectively interfering with cell cycle regulation, thus inhibiting the proliferation of cancer cells. CDK4-IN-4 is suitable for studies focusing on cell cycle dynamics and the therapeutic potential of CDK4 inhibition in various cancer models.
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SHIPPING AND STORAGE
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