Product Data Sheet
BMT-090605
Catalog No. A54497
BMT-090605 is a potent and selective inhibitor of adaptor protein-2 associated kinase 1 (AAK1), featuring an IC50 value of 0.6 nM. This compound exhibits significant antinociceptive activity and also demonstrates inhibitory effects on BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK), with IC50 values of 45 nM and 60 nM, respectively. BMT-090605 is a valuable tool for research into mechanisms underlying neuropathic pain.
Chemical Information
| Catalog Num | A54497 |
|---|---|
| M. Wt | 364.44 |
| Formula | C21H24N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1551403-51-0 |
| Synonyms | |
| SMILES | N#CC1=C(OC[C@@H](N)CC(C)C)C=C(C(C2=CC=NC(C)=C32)=C1)N(C)C3=O |
Biological Activity
| Description | BMT-090605 is a potent and selective inhibitor of adaptor protein-2 associated kinase 1 (AAK1), featuring an IC50 value of 0.6 nM. This compound exhibits significant antinociceptive activity and also demonstrates inhibitory effects on BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK), with IC50 values of 45 nM and 60 nM, respectively. BMT-090605 is a valuable tool for research into mechanisms underlying neuropathic pain. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
