Product Data Sheet

ZL-2201 free base

Catalog No. A54603

main product photo
ZL-2201 free base is a highly selective inhibitor of DNA-dependent protein kinase (DNA-PK), demonstrating an IC50 of 1 nM. This compound has significant implications in research applications focused on DNA repair mechanisms, cancer therapy, and radiation sensitization. ZL-2201 is ideal for studies investigating the modulation of DNA damage response pathways.
Chemical Information
Catalog NumA54603
M. Wt407.43
FormulaC19H21N9O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2646592-18-7
Synonyms
SMILESO=C1N(C)C2=CN=C(NC3=CN4C(C=C3C)=NC=N4)N=C2N1N5CC(O6)CCC6C5
Biological Activity
DescriptionZL-2201 free base is a highly selective inhibitor of DNA-dependent protein kinase (DNA-PK), demonstrating an IC50 of 1 nM. This compound has significant implications in research applications focused on DNA repair mechanisms, cancer therapy, and radiation sensitization. ZL-2201 is ideal for studies investigating the modulation of DNA damage response pathways.
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SHIPPING AND STORAGE
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