Product Data Sheet
Nemorubicin hydrochloride
Catalog No. A54691
Nemorubicin hydrochloride is a doxorubicin derivative that primarily targets G-quadruplex structures. It exhibits notable antitumor activity by intercalating into duplex DNA while also serving as a potent ligand for G-quadruplex DNA segments, effectively stabilizing their conformation. This compound is valuable for research applications focused on understanding G-quadruplex biology and developing therapeutic strategies targeting this unique DNA structure.
Chemical Information
| Catalog Num | A54691 |
|---|---|
| M. Wt | 680.10 |
| Formula | C32H38ClNO13 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 108943-08-4 |
| Synonyms | Methoxymorpholinyl doxorubicin hydrochloride; FCE 23762 hydrochloride; PNU 152243A |
| SMILES | COC1=C2C(C(C3=C(O)C(C[C@](C(CO)=O)(O)C[C@]4([H])O[C@H]5C[C@H](N6CCO[C@H](OC)C6)[C@H](O)[C@H](C)O5)=C4C(O)=C3C2=O)=O)=CC=C1.[H]Cl |
Biological Activity
| Description | Nemorubicin hydrochloride is a doxorubicin derivative that primarily targets G-quadruplex structures. It exhibits notable antitumor activity by intercalating into duplex DNA while also serving as a potent ligand for G-quadruplex DNA segments, effectively stabilizing their conformation. This compound is valuable for research applications focused on understanding G-quadruplex biology and developing therapeutic strategies targeting this unique DNA structure. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
