LDN-209929
Catalog No. A54697

LDN-209929 is a highly selective inhibitor of the haspin kinase, displaying an IC50 value of 55 nM for Haspin and 9.9 μM for DYRK2. This compound is utilized in research exploring the regulation of mitosis and cell division by specifically targeting the phosphorylation of histone H3. LDN-209929 serves as a valuable tool for investigating cancer biology and the mechanisms underlying various cell cycle-related processes.
Chemical Information
| Catalog Num | A54697 |
|---|---|
| M. Wt | 332.85 |
| Formula | C17H17ClN2OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1233355-57-1 |
| Synonyms | |
| SMILES | ClC1=CC2=C(N=C3C=CC(OC)=CC3=C2SCCCN)C=C1 |
Biological Activity
| Description | LDN-209929 is a highly selective inhibitor of the haspin kinase, displaying an IC50 value of 55 nM for Haspin and 9.9 μM for DYRK2. This compound is utilized in research exploring the regulation of mitosis and cell division by specifically targeting the phosphorylation of histone H3. LDN-209929 serves as a valuable tool for investigating cancer biology and the mechanisms underlying various cell cycle-related processes. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


