Product Data Sheet

IXA6

Catalog No. A54707

main product photo
IXA6 is a specific activator of IRE1, leading to the activation of XBP1s through the induction of IRE1 RNase activity. This compound plays a crucial role in regulating the unfolded protein response (UPR) and enhancing ER stress signaling pathways. IXA6 is valuable for research into cellular stress responses, protein folding mechanisms, and potential therapeutic interventions in diseases linked to ER dysfunction.
Chemical Information
Catalog NumA54707
M. Wt441.94
FormulaC22H20ClN3O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1021106-40-0
Synonyms
SMILESO=C(CN(S(=O)(C1=CC=CN=C1)=O)CC2=CC=C(C=C2)Cl)N3C4=C(CC3)C=CC=C4
Biological Activity
DescriptionIXA6 is a specific activator of IRE1, leading to the activation of XBP1s through the induction of IRE1 RNase activity. This compound plays a crucial role in regulating the unfolded protein response (UPR) and enhancing ER stress signaling pathways. IXA6 is valuable for research into cellular stress responses, protein folding mechanisms, and potential therapeutic interventions in diseases linked to ER dysfunction.
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SHIPPING AND STORAGE
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