Product Data Sheet
IXA62
Catalog No. A54711
IXA62 is an orally active and selective activator of IRE1/XBP1s, exhibiting an EC50 value of 0.31 μM. This compound is shown to reduce Aβ secretion, making it a potential candidate for research into Alzheimer's disease pathology. Additionally, IXA62 enhances glucose-stimulated insulin secretion in rat insulinoma cells, highlighting its applicability in studies of glucose metabolism and diabetes research.
Chemical Information
| Catalog Num | A54711 |
|---|---|
| M. Wt | 401.46 |
| Formula | C24H23N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 956783-34-9 |
| Synonyms | |
| SMILES | CN1C2=CC=CC=C2C(C(CN3C(NC(C4CC4)(C3=O)C)=O)=O)=C1C5=CC=CC=C5 |
Biological Activity
| Description | IXA62 is an orally active and selective activator of IRE1/XBP1s, exhibiting an EC50 value of 0.31 μM. This compound is shown to reduce Aβ secretion, making it a potential candidate for research into Alzheimer's disease pathology. Additionally, IXA62 enhances glucose-stimulated insulin secretion in rat insulinoma cells, highlighting its applicability in studies of glucose metabolism and diabetes research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
