Product Data Sheet
IRE1α kinase-IN-3
Catalog No. A54726
IRE1α kinase-IN-3 is a potent inhibitor of the inositol-requiring enzyme 1 alpha (IRE1α) with an inhibitory constant (Ki) of 480 nM. This compound acts as an ATP-competitive ligand, selectively targeting IRE1α to modulate its kinase activity. IRE1α kinase-IN-3 is valuable for studying the role of IRE1α in the unfolded protein response and related cellular processes, making it a useful tool for research in stress responses and related diseases.
Chemical Information
| Catalog Num | A54726 |
|---|---|
| M. Wt | 544.67 |
| Formula | C29H32N6O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2416223-41-9 |
| Synonyms | |
| SMILES | O=S(NC1=CC=CC2=C1C=CC=C2OC3=C(C4=NC(N[C@H]5CC[C@@H](CC5)N)=NC=C4)C=CC=N3)(C6CCC6)=O |
Biological Activity
| Description | IRE1α kinase-IN-3 is a potent inhibitor of the inositol-requiring enzyme 1 alpha (IRE1α) with an inhibitory constant (Ki) of 480 nM. This compound acts as an ATP-competitive ligand, selectively targeting IRE1α to modulate its kinase activity. IRE1α kinase-IN-3 is valuable for studying the role of IRE1α in the unfolded protein response and related cellular processes, making it a useful tool for research in stress responses and related diseases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
