LG157
Catalog No. A54754

LG157 is a potent inhibitor of mitotic kinesin-like protein 2 (MKLP2), a critical motor protein involved in maintaining mitotic spindle dynamics and cytokinesis. By selectively targeting MKLP2, LG157 effectively disrupts cell division, making it a valuable reagent for research into cancer cell proliferation and related therapeutic strategies. Its application in cell biology provides insight into the mechanisms of mitotic regulation and potential treatment approaches for tumors exhibiting aberrant cell division.
Chemical Information
| Catalog Num | A54754 |
|---|---|
| M. Wt | 349.38 |
| Formula | C20H19N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2840558-89-4 |
| Synonyms | |
| SMILES | CC1=NC=CC(C2=C(OC3=CC(C(NC)=O)=CC(OC)=C3)N=CC=C2)=C1 |
Biological Activity
| Description | LG157 is a potent inhibitor of mitotic kinesin-like protein 2 (MKLP2), a critical motor protein involved in maintaining mitotic spindle dynamics and cytokinesis. By selectively targeting MKLP2, LG157 effectively disrupts cell division, making it a valuable reagent for research into cancer cell proliferation and related therapeutic strategies. Its application in cell biology provides insight into the mechanisms of mitotic regulation and potential treatment approaches for tumors exhibiting aberrant cell division. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


