Product Data Sheet

MDI-114215

Catalog No. A54782

main product photo
MDI-114215 is an allosteric inhibitor targeting LIM Kinase 1 and 2 (LIMK1/2). It effectively inhibits the phosphorylation of cofilin in induced pluripotent stem cells (iPSCs) derived from mouse brain regions. This compound shows potential applications in research related to Fragile X Syndrome (FXS), enabling investigations into cellular pathways affected by LIMK activity.
Chemical Information
Catalog NumA54782
M. Wt479.59
FormulaC26H29N3O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3099003-91-2
Synonyms
SMILESO=C(N(CC1CC1)CC2=CC=C(NCCO)C=C2)C3=CC=C(S(=O)(NC4=CC=CC=C4)=O)C=C3
Biological Activity
DescriptionMDI-114215 is an allosteric inhibitor targeting LIM Kinase 1 and 2 (LIMK1/2). It effectively inhibits the phosphorylation of cofilin in induced pluripotent stem cells (iPSCs) derived from mouse brain regions. This compound shows potential applications in research related to Fragile X Syndrome (FXS), enabling investigations into cellular pathways affected by LIMK activity.
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