Product Data Sheet
CZh226
Catalog No. A54791
CZh226 is a selective inhibitor of PAK4 with an IC50 of 0.0111 μM and a Ki of 0.009 μM. This compound effectively inhibits PAK4 activity, leading to decreased phosphorylation of its downstream signaling molecules. CZh226 has demonstrated the ability to inhibit the migration and invasion of tumor cells, making it a valuable reagent for research related to lung cancer and other PAK4-mediated pathways.
Chemical Information
| Catalog Num | A54791 |
|---|---|
| M. Wt | 411.89 |
| Formula | C20H22ClN7O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2196199-00-3 |
| Synonyms | |
| SMILES | N(C=1C2=C(N=C(C(=O)N3C[C@@H](C)NCC3)N1)C=CC(Cl)=C2)C=4C=C(NN4)C5CC5 |
Biological Activity
| Description | CZh226 is a selective inhibitor of PAK4 with an IC50 of 0.0111 μM and a Ki of 0.009 μM. This compound effectively inhibits PAK4 activity, leading to decreased phosphorylation of its downstream signaling molecules. CZh226 has demonstrated the ability to inhibit the migration and invasion of tumor cells, making it a valuable reagent for research related to lung cancer and other PAK4-mediated pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
