Product Data Sheet
ER-076349
Catalog No. A54803
ER-076349 is a potent inhibitor of tubulin polymerization that effectively induces G2-M cell cycle arrest and disrupts mitotic spindle formation. This compound demonstrates significant anti-cancer activity by inhibiting the growth of various human tumor xenografts. As an analog of Halichondrin B, ER-076349 serves as a valuable reagent for research focused on cancer biology and therapeutic development targeting microtubule dynamics.
Chemical Information
| Catalog Num | A54803 |
|---|---|
| M. Wt | 730.88 |
| Formula | C40H58O12 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 253128-15-3 |
| Synonyms | Eribulin intermediate |
| SMILES | C=C1C[C@@](CC[C@@]2(C[C@@]3([H])O4)O[C@]([C@](O[C@](C5)([H])CC6)([H])[C@@]6([H])O7)([H])[C@@]4([H])[C@]7([H])[C@@]3([H])O2)([H])O[C@@]1([H])CC[C@](C[C@@H](C)C8=C)([H])O[C@]8([H])C[C@@](O[C@H](C[C@H](O)CO)[C@@H]9OC)([H])[C@]9([H])CC5=O |
Biological Activity
| Description | ER-076349 is a potent inhibitor of tubulin polymerization that effectively induces G2-M cell cycle arrest and disrupts mitotic spindle formation. This compound demonstrates significant anti-cancer activity by inhibiting the growth of various human tumor xenografts. As an analog of Halichondrin B, ER-076349 serves as a valuable reagent for research focused on cancer biology and therapeutic development targeting microtubule dynamics. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
