Product Data Sheet
Davunetide
Catalog No. A54807
Davunetide is a microtubule-stabilizing peptide derived from the activity-dependent neuroprotective protein (ADNP). It exhibits neuroprotective and neurotrophic properties, enhancing cognitive function. Davunetide selectively interacts with and stabilizes neuron-specific βIII-tubulin in vitro, facilitating structural integrity within neurons. Additionally, it penetrates the blood-brain barrier and demonstrates non-toxic characteristics while effectively inhibiting amyloid beta (Aβ) aggregation and the resultant neurotoxicity, making it valuable for research in neurodegenerative diseases.
Chemical Information
| Catalog Num | A54807 |
|---|---|
| M. Wt | 824.92 |
| Formula | C36H60N10O12 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 211439-12-2 |
| Synonyms | |
| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@@H](N)CC(N)=O)C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(O)=O |
Biological Activity
| Description | Davunetide is a microtubule-stabilizing peptide derived from the activity-dependent neuroprotective protein (ADNP). It exhibits neuroprotective and neurotrophic properties, enhancing cognitive function. Davunetide selectively interacts with and stabilizes neuron-specific βIII-tubulin in vitro, facilitating structural integrity within neurons. Additionally, it penetrates the blood-brain barrier and demonstrates non-toxic characteristics while effectively inhibiting amyloid beta (Aβ) aggregation and the resultant neurotoxicity, making it valuable for research in neurodegenerative diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
