Product Data Sheet

Paclitaxel-2′-succinate NHS ester

Catalog No. A54822

main product photo
Paclitaxel-2'-succinate NHS ester is a reactive paclitaxel derivative that features a succinic acid linker with a highly activated NHS ester group. This compound facilitates efficient conjugation with amino or hydroxyl groups, making it suitable for coupling with peptides, proteins, antibodies, enzymes, or polymers. Its applications extend to the development of innovative nanomedicines and the exploration of targeted strategies in cancer therapy.
Chemical Information
Catalog NumA54822
M. Wt1051.05
FormulaC55H58N2O19
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.245110-80-9
Synonyms
SMILESCC(O[C@]12[C@@]3([H])[C@@H]([C@]4(C(C)(C([C@H](C([C@@]3([C@H](C[C@@]1([H])OC2)O)C)=O)OC(C)=O)=C([C@H](C4)OC([C@H](OC(CCC(ON5C(CCC5=O)=O)=O)=O)[C@H](C6=CC=CC=C6)NC(C7=CC=CC=C7)=O)=O)C)C)O)OC(C8=CC=CC=C8)=O)=O
Biological Activity
DescriptionPaclitaxel-2'-succinate NHS ester is a reactive paclitaxel derivative that features a succinic acid linker with a highly activated NHS ester group. This compound facilitates efficient conjugation with amino or hydroxyl groups, making it suitable for coupling with peptides, proteins, antibodies, enzymes, or polymers. Its applications extend to the development of innovative nanomedicines and the exploration of targeted strategies in cancer therapy.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.