Product Data Sheet

Monomethyl auristatin E intermediate-7

Catalog No. A54823

main product photo
Monomethyl auristatin E intermediate-7 is a key intermediate in the synthesis of Monomethyl auristatin E (MMAE), a potent microtubule/tubulin inhibitor with established anticancer properties. MMAE serves as a cytotoxic component in antibody-drug conjugates (ADCs), which are utilized in targeted cancer therapies. This reagent is essential for researchers engaged in the development and optimization of ADC formulations aimed at enhancing therapeutic efficacy in oncology.
Chemical Information
Catalog NumA54823
M. Wt365.46
FormulaC20H31NO5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.135383-55-0
Synonyms
SMILESCC[C@H](C)[C@@H]([C@@H](CC(OC(C)(C)C)=O)O)NC(OCC1=CC=CC=C1)=O
Biological Activity
DescriptionMonomethyl auristatin E intermediate-7 is a key intermediate in the synthesis of Monomethyl auristatin E (MMAE), a potent microtubule/tubulin inhibitor with established anticancer properties. MMAE serves as a cytotoxic component in antibody-drug conjugates (ADCs), which are utilized in targeted cancer therapies. This reagent is essential for researchers engaged in the development and optimization of ADC formulations aimed at enhancing therapeutic efficacy in oncology.
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