Product Data Sheet
AMXI-5001
Catalog No. A54837
AMXI-5001 is a potent, orally active dual inhibitor of PARP1/2 and microtubule polymerization. This compound demonstrates selective antitumor cytotoxicity in various human cancer cell lines, exhibiting lower IC50 values compared to existing clinical PARP inhibitors. AMXI-5001 is capable of inducing complete regression of established tumors, including those of considerable size, making it a promising candidate for cancer research and therapeutic development.
Chemical Information
| Catalog Num | A54837 |
|---|---|
| M. Wt | 457.46 |
| Formula | C25H20FN5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2170491-77-5 |
| Synonyms | |
| SMILES | O=C(NC1=NC2=C(N1)C=C(C3=C(F)C=CC(CC4=NNC(C5=C4C=CC=C5)=O)=C3)C=C2)OCC |
Biological Activity
| Description | AMXI-5001 is a potent, orally active dual inhibitor of PARP1/2 and microtubule polymerization. This compound demonstrates selective antitumor cytotoxicity in various human cancer cell lines, exhibiting lower IC50 values compared to existing clinical PARP inhibitors. AMXI-5001 is capable of inducing complete regression of established tumors, including those of considerable size, making it a promising candidate for cancer research and therapeutic development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
