Product Data Sheet

Carba1

Catalog No. A54855

main product photo
Carba1 is a bifunctional carbazole derivative that acts as an activator of nicotinamide phosphoribosyltransferase (NAMPT), thereby enhancing NAD biosynthesis. This compound also binds to the colchicine site of tubulin, which can potentiate the anticancer effects of various chemotherapeutic agents, including Paclitaxel. Additionally, Carba1 displays neuroprotective properties and is capable of modulating cellular energy metabolism. It is suitable for research applications focused on cancer therapies and chemotherapy-induced peripheral neuropathy (CIPN).
Chemical Information
Catalog NumA54855
M. Wt294.78
FormulaC18H15ClN2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2635394-10-2
Synonyms
SMILESCC1=CC(N2C=CC=C2)=C(C)C3=C1NC4=C3C=C(Cl)C=C4
Biological Activity
DescriptionCarba1 is a bifunctional carbazole derivative that acts as an activator of nicotinamide phosphoribosyltransferase (NAMPT), thereby enhancing NAD biosynthesis. This compound also binds to the colchicine site of tubulin, which can potentiate the anticancer effects of various chemotherapeutic agents, including Paclitaxel. Additionally, Carba1 displays neuroprotective properties and is capable of modulating cellular energy metabolism. It is suitable for research applications focused on cancer therapies and chemotherapy-induced peripheral neuropathy (CIPN).
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