Product Data Sheet
Tubulin polymerization-IN-47
Catalog No. A54857
Tubulin polymerization-IN-47 is a potent inhibitor of tubulin polymerization, specifically targeting mitotic processes. This compound demonstrates significant inhibitory effects on neuroblastoma cancer cell proliferation, exhibiting IC50 values of 7 nM and 12 nM against the Chp-134 and Kelly cell lines, respectively. It is a valuable tool for research in cancer biology, particularly in the study of cell division and the mechanisms of tumor growth.
Chemical Information
| Catalog Num | A54857 |
|---|---|
| M. Wt | 375.42 |
| Formula | C22H21N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2834087-62-4 |
| Synonyms | |
| SMILES | COC1=CC(C2=NC=CN3C=C(C4=CC=C(C)C=C4)N=C32)=CC(OC)=C1OC |
Biological Activity
| Description | Tubulin polymerization-IN-47 is a potent inhibitor of tubulin polymerization, specifically targeting mitotic processes. This compound demonstrates significant inhibitory effects on neuroblastoma cancer cell proliferation, exhibiting IC50 values of 7 nM and 12 nM against the Chp-134 and Kelly cell lines, respectively. It is a valuable tool for research in cancer biology, particularly in the study of cell division and the mechanisms of tumor growth. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
