Product Data Sheet
PM534
Catalog No. A54865
PM534 is a tubulin-targeting agent that inhibits tubulin assembly with IC50 values ranging from 0.8 to 3.2 nM. By binding to the colchicine site of tubulin, PM534 disrupts microtubule dynamics, demonstrating significant antitumor activity. This compound is valuable for research applications in cancer biology, particularly in studies focused on cell division and microtubule-targeting therapies.
Chemical Information
| Catalog Num | A54865 |
|---|---|
| M. Wt | 421.51 |
| Formula | C20H27N3O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2446376-25-4 |
| Synonyms | |
| SMILES | O=C([C@]1(N=C(SC1)/C(C)=N/O)C)N[C@@H](C2=CC(OCC3CC3)=CC(O2)=O)CCC |
Biological Activity
| Description | PM534 is a tubulin-targeting agent that inhibits tubulin assembly with IC50 values ranging from 0.8 to 3.2 nM. By binding to the colchicine site of tubulin, PM534 disrupts microtubule dynamics, demonstrating significant antitumor activity. This compound is valuable for research applications in cancer biology, particularly in studies focused on cell division and microtubule-targeting therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
