Product Data Sheet
Deacetoxyvinzolidine
Catalog No. A54874
Deacetoxyvinzolidine is a bis-indole derivative that functions as an anti-microtubular agent by disrupting microtubule assembly. It demonstrates a strong affinity for bovine purified brain tubulin, with a Kd of 3 μM, effectively inhibiting microtubule formation at concentrations as low as 10 nM. Its significant anti-tumoral properties make it a valuable tool for research, particularly in the investigation of leukemia and related malignancies.
Chemical Information
| Catalog Num | A54874 |
|---|---|
| M. Wt | 826.42 |
| Formula | C46H56ClN5O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 165659-77-8 |
| Synonyms | KAR-2 |
| SMILES | CN1[C@]2([H])[C@]3(C4=CC([C@@]5(C6=C(CC[N@@]7C[C@](C[C@](O)(C7)CC)([H])C5)C8=CC=CC=C8N6)C(OC)=O)=C(OC)C=C41)[C@]9([H])[C@](C[C@]2%10C(N(C(O%10)=O)CCCl)=O)(C=CCN9CC3)CC |
Biological Activity
| Description | Deacetoxyvinzolidine is a bis-indole derivative that functions as an anti-microtubular agent by disrupting microtubule assembly. It demonstrates a strong affinity for bovine purified brain tubulin, with a Kd of 3 μM, effectively inhibiting microtubule formation at concentrations as low as 10 nM. Its significant anti-tumoral properties make it a valuable tool for research, particularly in the investigation of leukemia and related malignancies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
