Product Data Sheet
Microtubule inhibitor 3
Catalog No. A54916
Microtubule Inhibitor 3 targets tubulin, disrupting microtubule dynamics and resulting in cytotoxic activity against diverse human cancer cell lines. With an IC50 value of 14.0 nM in NCI-H460 cells, this compound, along with its analogs, demonstrates potent efficacy in inhibiting cell proliferation. Its applications extend to cancer research, particularly in studying microtubule-targeted therapies.
Chemical Information
| Catalog Num | A54916 |
|---|---|
| M. Wt | 458.48 |
| Formula | C26H23FN4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1236141-96-0 |
| Synonyms | |
| SMILES | CC(C)(C1=C(N=CN1)/C=C2NC(/C(NC\2=O)=C/C3=CC(C(C4=CC=C(C=C4)F)=O)=CC=C3)=O)C |
Biological Activity
| Description | Microtubule Inhibitor 3 targets tubulin, disrupting microtubule dynamics and resulting in cytotoxic activity against diverse human cancer cell lines. With an IC50 value of 14.0 nM in NCI-H460 cells, this compound, along with its analogs, demonstrates potent efficacy in inhibiting cell proliferation. Its applications extend to cancer research, particularly in studying microtubule-targeted therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
