Product Data Sheet
IKP-104
Catalog No. A54924
IKP-104 is a potent tubulin inhibitor with an IC50 of 1.31 μM, targeting microtubule polymerization to arrest cells in mitosis during the M phase. This compound induces cytoskeletal microtubule depolymerization, effectively inhibiting the growth of various mouse and human tumor cell lines. Additionally, IKP-104 demonstrates notable anti-tumor effects in mouse ascites tumors and lung cancer models, making it a valuable tool for research in leukemia, lung cancer, and melanoma.
Chemical Information
| Catalog Num | A54924 |
|---|---|
| M. Wt | 449.90 |
| Formula | C26H21ClFNO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 114231-14-0 |
| Synonyms | |
| SMILES | O=C1C(C)=C(C2=CC=C(F)C=C2)N(C3=CC(OC)=CC(OC)=C3Cl)C(C4=CC=CC=C4)=C1 |
Biological Activity
| Description | IKP-104 is a potent tubulin inhibitor with an IC50 of 1.31 μM, targeting microtubule polymerization to arrest cells in mitosis during the M phase. This compound induces cytoskeletal microtubule depolymerization, effectively inhibiting the growth of various mouse and human tumor cell lines. Additionally, IKP-104 demonstrates notable anti-tumor effects in mouse ascites tumors and lung cancer models, making it a valuable tool for research in leukemia, lung cancer, and melanoma. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
