Product Data Sheet
Antitumor agent-67
Catalog No. A54925
Antitumor agent-67 functions primarily as an antitumor agent with a specific mechanism of selectively targeting cancer cells. It demonstrates significant cytotoxicity towards tumor cells while exhibiting minimal effects on normal cells. The compound is activated by NQO1, which facilitates the release of podophyllotoxin, leading to effective tumor cell death. In preclinical studies, antitumor agent-67 has shown notable efficacy in inhibiting tumor growth in HepG2 xenograft models, with an advantageous toxicity profile.
Chemical Information
| Catalog Num | A54925 |
|---|---|
| M. Wt | 809.85 |
| Formula | C45H47NO13 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2820146-10-7 |
| Synonyms | |
| SMILES | O=C(OCC1=CC=C(N(C)C(CC(C2=C(C)C(C(C)=C(C)C2=O)=O)(C)C)=O)C=C1)O[C@H]3[C@]4([H])[C@@](C(OC4)=O)([H])[C@H](C5=CC(OC)=C(OC)C(OC)=C5)C6=C3C=C7OCOC7=C6 |
Biological Activity
| Description | Antitumor agent-67 functions primarily as an antitumor agent with a specific mechanism of selectively targeting cancer cells. It demonstrates significant cytotoxicity towards tumor cells while exhibiting minimal effects on normal cells. The compound is activated by NQO1, which facilitates the release of podophyllotoxin, leading to effective tumor cell death. In preclinical studies, antitumor agent-67 has shown notable efficacy in inhibiting tumor growth in HepG2 xenograft models, with an advantageous toxicity profile. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
